ON PYRIDINE HEMOCHROMOGEN

On Pyridine Hemochromogen

1. Cyanide hemochromogen probably contains one cyanide group per heme group. 2. The equilibrium between pyridine hemochromogen and its components, pyridine and reduced heme, is complicated to an unknown extent by the precipitation of reduced heme and the aggregation of pyridine hemochromogen. 3. These complications were not taken into account in R. Hill's experiments on pyridine hemochromogen. ...

On Hemochromogen

1. Every hemochromogen consists of the iron pyrrol complex, reduced heme, combined with some nitrogenous substance. 2. In every hemochromogen there is the equilibrium: Hemochromogen right arrow over left arrow Reduced heme + Nitrogenous substance. 3. Cyanide can form two distinct compounds with reduced heme, one of which is the typical hemochromogen, cyan-hemochromogen. 4. Reduced heme in alkal...

The Reactions of Cyanide with Globin Hemochromogen

Cyanide can react with globin hemochromogen in two different ways. In the first reaction cyanide combines with globin hemochromogen without displacing or competing with globin. In the second reaction cyanide displaces globin.

A Hemochromogen Component of Liver Microsomes.

A Method for the Quantitative Determination of Hemoglobin and Related Heme Pigments in Feces, Urine, and Blood Plasma*

The purpose of the present study was to make available a simple quantitative procedure for total heme pigments in feces, urine, and blood plasma or serum. It was planned to convert these substances to pyridine ferrohemochromogen, which is known to have stronger absorption than other easily prepared heme compounds, and to measure this absorption under standard conditions with the Evelyn photoele...